beta 2-Microglobulin

An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.

Also Known As:

beta 2 Microglobulin; Thymotaxin

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        beta 2-Microglobulin: 1689
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        beta 2-Microglobulin: 1689
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Beta-Globulins: 159
        beta 2-Microglobulin: 1689
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        beta 2-Microglobulin: 1689
  - Globulins: 3062
    - Serum Globulins: 553
      - Beta-Globulins: 159
        beta 2-Microglobulin: 1689
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - Histocompatibility Antigens Class I: 1944
        beta 2-Microglobulin: 1689
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - Histocompatibility Antigens Class I: 1944
        beta 2-Microglobulin: 1689

A A Molodyk Selected Research

A A Molodyk Research Topics

Disease

Drug/Important Bio-Agent (IBA)